IVF for Unexplained Infertility

If you’ve been trying to conceive and your test results are all “normal,” yet there’s still no pregnancy, it might be what doctors call unexplained infertility. It’s a confusing label that offers no clear reason, only more questions. Many couples describe this stage as emotionally exhausting. But you’re not without options. IVF can be a turning point. The Steps of the IVF Process are way more than just a treatment, but a life-changing event offering renewed hope when nothing else has worked.

Why is IVF often Recommended for Unexplained infertility?

When you’re told you have unexplained infertility, you may panic. It doesn't mean nothing is right, but it just means we haven't found what's wrong, and that's the hardest part. You’ve done the tests, tried the usual advice, been on medicines, have timed cycles, yet nothing has helped. Here IVF in unexplained infertility will help;

• IVF detects problems that tests don’t pick up, like subtle egg quality issues.

• The fertilisation process happens outside the body, giving us more control.

• Embryo selection is based on development, not just hope.

  
  

  IVF isn't always easy and fast, but for couples with unexplained infertility, it can be a meaningful next step. It doesn’t fix unexplained infertility, but it can help you move forward with more clarity and hope.
  

How IVF Works in Unexplained Infertility?

For couples dealing with unexplained infertility, IVF gives a clearer, more hands-on approach. It's finally a process that lets doctors see what's going on.

IVF begins with ovarian stimulation. Women go through hormone injections to encourage their ovaries to grow several eggs instead of just one. And once the eggs are ready, they are retrieved under light sedation.

Further, a medical expert, likely a Perniologist, fertilises those eggs in a lab using ICSI. This process involves injecting a single sperm into each egg directly to improve the chances of fertilisation. Later, specialists monitor embryo development. They notice sperm-egg compatibility or embryo quality, which regular tests fail to show.

Once a healthy embryo is detected, our expert doctors in Bliss Fertility places it into the woman's uterus through a simple embryo transfer procedure.

Before moving towards transfer, some couples also choose preimplantation genetic testing (PGT). While it isn't a mandatory step, it can help you find if there are any chromosomal issues in the embryos.

Success Rates of IVF for Unexplained infertility.

IVF is one of the most popular and used treatments for unexplained infertility, as it often delivers better odds. Age‑based IVF success (live birth per fresh cycle):

• Under 29: ~78%

• Age 30–34: ~67%

• Age 35-39: ~49%

• Age 40–44: ~29%

• Over 45: ~15%
  

IUI, by contrast, typically achieves lower rates and fewer live births per cycle:

• Under 35: ~16%

• Age 35–39: ~11%

• Age 40–42: ~4.7%

• Over 43: ~1%
  

In practical terms, that’s roughly double the success rate with IVF versus IUI in most age groups.

What Makes IVF a Stronger Choice for Unexplained Infertility?

According to clinical reviews, IUI with ovarian stimulation is effective for treatment-naive couples. In contrast, IVF is more suitable for a live‑birth rate 2 to 3 times higher for those who’ve already tried IUI without success.

Couples who are stuck without any obvious diagnosis not only get clarity, but IVF also raises the odds per cycle, while uncovering hidden issues and avoiding the trial‑and‑error of multiple IUI attempts.

What Are the Alternatives to IVF, and When to Consider IVF for Unexplained Infertility?

If no specific cause is found, couples with unexplained infertility often start with less invasive options: timed intercourse, ovulation induction. Many experts also suggest expectant management, since up to 50% of couples may conceive naturally in the second year of trying.

Guidelines generally recommend moving to IVF:

• After about 12 months of trying if under 35

• After 6 months if over 35.

• Or soon if been trying and failing for 2 or more years.
  

If you fall into these categories, IVF may offer a more structured and effective path. It’s a next step when simpler options haven’t worked, time is moving on, and fertility potential may be declining.

How Can You Navigate the IVF Journey with Realistic Expectations and Support?

IVF isn't a guaranteed fix for unexplained pregnancy, and that's very important to know. It does offer a structured and hopeful path forward, but success for everyone can vary. Factors like age, egg quality, and overall health can vary widely. Similarly, the emotional journey is equally important. As per Bliss Fertility’s research, psychological support such as counseling, partner closeness, and peer groups can reduce stress, improve mental resilience and improve the quality of pregnancy.

So, Is IVF for Unexplained Infertility Right for You?

Whether IVF in Unexplained Infertility is right for you, it's totally up to you. It is crucial to know that this process is not an easy one and it only happens without guarantees. But if the waiting is wearing you down, it may be worth trying. Don't let Unexplained Infertility stop you from your dream of starting a family If you're ready to take the next step and understand how IVF can work for you, our expert team at Bliss Fertility is here to help you. So, put your worries aside and contact us today to book your consultation.  Call Now

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